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“For many people, office work involves extended periods of time at their desk. For some, it can be all day. Despite the growing availability of ergonomic products and workplace offerings like flexible gym hours, scientists believe many desk jockeys will have already done lasting damage to their bodies as a result of sitting down all day,” according to Business Insider.

Said Peter T. Katzmarzyk, Ph.D.: “Even within physically active individuals, there was a strong association between sitting and risk of mortality… This is an important observation because it suggests that high amounts of sitting cannot be compensated for with occasional leisure time physical activity even if the amount exceeds the current minimum physical activity recommendations.”

The article lists 11 “adverse effects” on the body — ranging from low energy and compromised posture to back injuries and depression — that can occur from sitting at your desk for too long.

Meanwhile, USA Today reports that sitting too much “may increase the risk of disability in people over age 60, a new study suggests.”